Paracetamol is extremely toxic to cats, which lack the necessary glucuronyl transferase enzymes to safely break it down.
Initial symptoms include vomiting,salivation,discoloration of the tongue and gums.
Unlike an overdose in humans, liver damage is rarely the cause of death; instead, methemoglobin formation and the production of Heinz bodies in red blood cells inhibit oxygen transport by the blood, causing asphyxiation (methemoglobemia and hemolytic anemia).
Treatment with N-acetylcysteine,methylene blue or both is sometimes effective after the ingestion of small doses of paracetamol.
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